Residents in eastern Illinois and northern Indiana should prepare for severe weather conditions, including the possibility of isolated tornadoes. Areas east of Interstate 57 are particularly vulnerable to the worst impacts, which may include damaging winds over 60 mph and hail. Supercell storms could exacerbate risks, especially during the mid-to-late afternoon hours on Wednesday. While the rest of the Chicago area faces a lower risk, scattered showers and thunderstorms remain possible.